For a number of reasons, I have replaced the backing ORM. Previously I was using peewee, but now I’m using PonyORM. The primary reason for this is purely ideological; I do not want to use software which is maintained by someone with a track record of toxic behavior. peewee’s maintainer responds to issues and feature requests with shouting and dismissive snark; PonyORM’s maintainer responds with helpfulness and grace. I am a strong proponent of the latter.
PonyORM’s API is also significantly more Pythonic, and rather than abusing operator overloads for clever query building purposes, it abuses Python’s AST functionality to parse actual Python expressions into SQL queries. Seriously, look at this explanation of it and tell me that isn’t just amazing.